Human health

Scientific consensus on the potential harmfulness of animal-sourced foods cannot be claimed

Dietary recommendations to limit the consumption of animal source foods, especially red and processed meats, are based on the assumption that their intake leads to chronic diseases. However, there is no clear scientific consensus on this matter. The evidence is of low certainty and subject to problematic interpretations. High-quality evidence is obtained when epidemiology, randomized controlled trials, experimental models, and mechanistic explanations agree with one another. This is far from being the case. 

Even if some (but certainly not all) observational studies suggest that small increases in absolute risk of certain chronic diseases may take place, this is insufficient to be confident about a causal relationships between food intake and health. Secondly, there is no robust evidence from human intervention trials in support of causality, as the most pertinent biomarkers do not seem to be negatively affected. Thirdly, animal studies and other experimental models have not adequately demonstrated plausible mechanisms to explain potential harm in the context of healthy background diets. 

It is improbable that consuming foods to which the human body has adapted evolutionarily would lead to so-called 'diseases of modernity'. Thus, the entire argument that eating certain animal source foods may lead to chronic disease is overstated. When evaluating the totality of the available evidence, there is no reason to assume risk when animal source foods are part of wholesome dietary patterns. Limiting their consumption could even compromise the intake of priority nutrients, which might be worse for health than any potential chronic illness that may be linked to consuming these foods.

What are the dietary recommendations saying?


Dietary recommendations often advocate for limiting the consumption of animal source foods, particularly red and processed meats, as well as animal fat. Some authors even categorize animal source foods as 'less healthy' compared to plant-derived foods, and equate red meat with unhealthy foods like sugar. However, contrary to claims made by vocal public health nutritionists, these recommendations lack consensus and unanimous scientific support. 

Some experts have expressed concerns, especially for populations with high nutritional needs. They argue that these recommendations rely on incomplete data and problematic interpretations. Moreover, overly restricting animal source foods may lead to nutrient deficiencies that outweigh any potential risk of chronic disease.

Why is the case against animal-sourced foods overstated?


Observational studies suggest that consuming certain animal-source foods may be linked to slightly increased health risks. However, these findings remain contentious, plagued by confounding factors and bias. Intervention studies have largely failed to support these associations, and biochemical research has yet to identify clear mechanisms to explain them.

Researchers recognize these limitations and caution against overinterpreting results, highlighting issues such as heterogeneity and residual confounding. Similarly, the WHO/IARC panel investigating the link between red meat consumption and colorectal cancer emphasized the role of chance, bias, or confounding and did not establish red meat as a definitive cause of cancer.

Nonetheless, some of the more influential and activistic studies and reports present unjustified causal claims and recommendations, which are then uncritically adopted in policy frameworks.

Why is advice to specifically limit red meat not supported?


Influential organizations, including the WCRF, WHO, IARC, EAT-Lancet Commission, the Nordic Nutritional Recommendations committee, and the Global Burden of Diseases consortium, are alarmist about the potential health risks associated with red and processed meats, for which they argue restriction. While these organizations position themselves as authoritative, their claims have faced severe criticism on methodological grounds from various scientists.

Concerns include poor data quality and weak evidence. Regional inconsistencies are also notable, with cohorts in the USA often showing worse outcomes, suggesting cultural or dietary biases in the data. In contrast, the PURE study, a large global dietary cohort, indicates that unprocessed red meat should not be a target for reduction, with higher intake levels correlating with better health outcomes.

The GRADE system, the gold standard for evaluating epidemiological evidence, concludes that there is only 'low' to 'very-low' certainty that reducing red and processed meat intake improves cancer mortality, cardiometabolic outcomes, or overall mortality. Consequently, it offers a recommendation for adults to maintain rather than restrict their current consumption levels, emphasizing the importance of individual decision-making based on absolute effect estimates.

Vocal nutritionists with a strong anti-meat bias have tried to dismiss this criticism by launching an unsubstantiated smear campaign against dissident voices and by arguing that GRADE is too severe, thereby stating that they are ready to accept substandard evidence for nutritional epidemiology.

How to evaluate the 'risk' of animal-sourced foods in the diet?


The reporting of 'relative' risks (RR) associated with the intake of animal-sourced foods in relation to health outcomes often leads to unwarranted sensationalism. These values are frequently presented without mentioning the 'absolute' risk (AR), creating exaggerated interpretations among non-experts. Even dietary guidelines tend to overlook the trivial AR reductions that come with dietary changes. 

For instance, an 18% RR increase for colorectal cancer linked to high processed meat consumption sounds alarming, but its corresponding AR increase is only 1%. To put it differently, the likelihood of someone not developing colorectal cancer during their lifetime would only shift from 94% to 93% with such a dietary change. Moreover, this virtual risk increase is based on low-certainty evidence only.

Recommended resources


  • Johnston et al. (2019) Unprocessed red meat and processed meat consumption: dietary guideline recommendations from the Nutritional Recommendations (NutriRECS) Consortium. Annals of Internal Medicine.
  • Johnston et al. (2023) Non-communicable disease risk associated with red and processed meat consumption—magnitude, certainty, and contextuality of risk? Animal Frontiers.
  • Leroy & Cofnas (2020) Should dietary guidelines recommend low red meat intake. Critical Reviews in Food Science and Nutrition.
  • Mente et al. (2023) Diet, cardiovascular disease, and mortality in 80 countries. European Heart Journal.
  • Rubin (2020) Backlash Over Meat Dietary Recommendations Raises Questions About Corporate Ties to Nutrition Scientists. Journal of the American Medical Association.
  • Stanton (2024) Unacceptable use of substandard metrics in policy decisions which mandate large reductions in animal-source foods. npj Science of Food.
  • Stanton et al. (2022) 36-fold higher estimate of deaths attributable to red meat intake in GBD 2019: is this reliable? The Lancet.

Correlation between red and processed meat consumption and health risk


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